Acid Reflux Research Today is a free monthly online journal that collates and summarizes the latest research about Acid Reflux, including details on diet, gerd (gastro-esophageal reflux disease), treatment, symptoms.

Reflux monitoring: role of combined multichannel intraluminal impedance and pH.

Tutuian R, Castell DO

Division of Gastroenterology/Hepatology, Medical University of South Carolina, 96 Jonathan Lucas Street, 210 CSB, Charleston, SC 29425, USA. tutuianr@musc.edu

Combined multichannel intraluminal impedance and pH (MII-pH) is a promising technique that identifies liquid, gas, and mixed gastroesophageal reflux and categorizes it into acid and nonacid types. Gastroesophageal monitoring using combined MII-pH reconfirms previously reported data that there is a difference between refluxate volume presence time in the esophagus and time pH less than 4. Only one in five patients with persistent symptoms on acid-suppressive therapy have symptoms associated with persistent acid reflux, whereas two of five patients have symptoms associated with nonacid reflux; the remaining patients do not have any type of GER related to their symptoms. Combined MII-pH is a useful tool in evaluating patients with persistent symptoms on acid-suppressive therapy, patients with atypical symptoms, and infants.

Published 21 February 2005 in Gastrointest Endosc Clin N Am, 15(2): 361-71.
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